Cardiovascular & Cardiometabolic Panel
Over 50% of premature cardiovascular events have an underlying hereditary component. This panel examines genes linked to Familial Hypercholesterolemia (FH), hypertrophic and dilated cardiomyopathies, thoracic aortic aneurysms, and cardiac channelopathies—giving your physician the clinical data necessary to protect your cardiovascular health proactively.
Check If You Qualify
Takes under 2 minutes • 100% Covered under Medicare Part B
Who Should Consider This Screening?
Healthcare providers recommend this diagnostic panel for individuals with the following personal or family health indicators:
Biomarkers & Genes Evaluated in this Panel
Processed using high-complexity Next-Generation Sequencing (NGS) in CLIA-certified and CAP-accredited partner laboratories.
| Gene Symbol / Name | Clinical Significance | Actionable Impact |
|---|---|---|
| LDLR, APOB, PCSK9Familial Hypercholesterolemia Clearance Trio | Regulates LDL cholesterol uptake and lifelong arterial plaque accumulation rates. | Qualifies patients for high-potency statins or advanced PCSK9 inhibitor therapies to dramatically lower cardiac event risks. |
| MYH7 & MYBPC3Cardiac Sarcomere Structural Proteins | Primary genetic drivers of hypertrophic and dilated cardiomyopathy. | Directs regular echocardiograms, Holter monitoring, and personalized exercise/exertion safety boundaries. |
| KCNQ1 & SCN5ACardiac Ion Channel Conductors | Linked to Long QT Syndrome, Brugada syndrome, and familial arrhythmia predispositions. | Prevents sudden cardiac events by avoiding contraindicated QT-prolonging medications and guiding beta-blocker therapy. |
Sample Report & Diagnostic Action Plan
Every patient receives an easy-to-understand diagnostic summary and a detailed clinical report tailored for their primary care doctor.
Pathogenic variant detected in LDLR (c.1775G>A, p.Gly592Glu) consistent with Familial Hypercholesterolemia.
Recommend intensive lipid-lowering therapy, baseline coronary artery calcium (CAC) scan, and cascade screening for first-degree family members.
Medicare Part B Coverage Guidelines
Understand how federal CMS medical necessity guidelines apply to this specific diagnostic screening:
Medicare Part B covers cardiovascular genetic testing when ordered by a physician for patients with clinical indicators of familial hypercholesterolemia, inherited arrhythmias, or family history of premature heart disease.
Ready to Check Your Eligibility for Cardiovascular & Cardiometabolic Panel?
Takes under 2 minutes • Painless at-home cheek swab • 100% Physician Reviewed

